Nicoduce (Nicorandil) Tablets are used to prevent or reduce painful signs (“angina pectoris”) of your heart disease. It is used in adults who cannot take heart medicines called “beta-blockers” or “calcium antagonists”.
Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP. Nicorandil is a vasodilatory drug used to treat angina. Angina is chest pain that results from episodes of transient myocardial ischemia. This can be caused by diseases such as atherosclerosis, coronary artery disease and aortic stenosis. Angina commonly arises from vasospasm of the coronary arteries.
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