is an immunosuppressive disease-modifying antirheumatic drug (DMARD),
used in active moderate-to-severe rheumatoid arthritis and psoriatic
arthritis. It is a pyrimidine synthesis inhibitor that works by
inhibiting dihydroorotate dehydrogenase. it is used alone or in
combination with other medications to treat rheumatoid arthritis (a
condition in which the body attacks its own joints, causing pain,
swelling, and loss of function).
Leflunomide can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.
Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, increased liver enzymes, and respiratory tract infection. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor of all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or effecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.
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